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<p>A theoretical and simulated method-based surface plasmon resonance (SPR) sensor has been proposed for the breast cancer detection by utilizing the phenomena of optimum radiation damping (ORD). The proposed sensor consists of CaF<sub>2</sub> prism as light coupler, silver (Ag) as plasmonic metal, silicon nitride (Si<sub>3</sub>N<sub>4</sub>) as absorption enhancement layer, and analyte medium. The investigation is performed using transfer matrix method in near to infrared (NIR) region. 2D simulation technique is used in which the figure-of-merit (FOM) of the sensor is enhanced by simultaneously varying the thickness of the materials used in sensor. The structure uses Ag layer (d<sub>M</sub>) and Si<sub>3</sub>N<sub>4</sub> layer (d<sub>A</sub>) under optimum radiation damping (ORD). An optimized FOM as high as 3670 RIU<sup>−1</sup> is achieved at d<sub>M</sub> to be 32.6&#xa0;nm and value of d<sub>A</sub> used is 3.3&#xa0;nm for wavelength (λ) equals to 1000&#xa0;nm. The corresponding power loss ratio (PLR) at ORD is as high as 4.078 and normalized electric field is 1.17. The combined performance factor (CPF) is given as 17,476 RIU<sup>−1</sup>. The proposed application of Si<sub>3</sub>N<sub>4</sub> in a plasmonic sensor utilized under ORD conditions significantly improves sensing performance and has been investigated as the most effective method for detecting breast cancer.</p>

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Near-Infrared Breast Cancer Detection Using Si₃N₄-Based Plasmonic Sensor Under an Optimum Radiation Damping

  • 期刊论文

  • 发表日期：

    2025年3月13日

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  • Anuradha Mishra,
  • Adarsh Chandra Mishra,
  • Sudhir Shukla,
  • Pooja Lohia,
  • D. K. Dwivedi,
  • Sapana Yadav,
  • R. K. Yadav,
  • Mohamed H. H. Mahmoud,
  • M. Khalid Hossain

摘要

A theoretical and simulated method-based surface plasmon resonance (SPR) sensor has been proposed for the breast cancer detection by utilizing the phenomena of optimum radiation damping (ORD). The proposed sensor consists of CaF2 prism as light coupler, silver (Ag) as plasmonic metal, silicon nitride (Si3N4) as absorption enhancement layer, and analyte medium. The investigation is performed using transfer matrix method in near to infrared (NIR) region. 2D simulation technique is used in which the figure-of-merit (FOM) of the sensor is enhanced by simultaneously varying the thickness of the materials used in sensor. The structure uses Ag layer (dM) and Si3N4 layer (dA) under optimum radiation damping (ORD). An optimized FOM as high as 3670 RIU−1 is achieved at dM to be 32.6 nm and value of dA used is 3.3 nm for wavelength (λ) equals to 1000 nm. The corresponding power loss ratio (PLR) at ORD is as high as 4.078 and normalized electric field is 1.17. The combined performance factor (CPF) is given as 17,476 RIU−1. The proposed application of Si3N4 in a plasmonic sensor utilized under ORD conditions significantly improves sensing performance and has been investigated as the most effective method for detecting breast cancer.