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<p>Diabetic polyneuropathy is one of the most common chronic complications of diabetes with a&#xa0;major impact on mortality and quality of life, yet it remains a&#xa0;frequently overlooked and undertreated condition in clinical practice. It is typically characterized by a&#xa0;progressive distal to proximal loss of sensation in the lower extremity and, in around 50% of cases, with neuropathic symptoms in this area. A&#xa0;careful exclusion of other causes and efficient standardized clinical assessments aid in screening and a&#xa0;timely diagnosis. Strategies for prevention and treatment include the reduction of risk factors, pathogenetically-oriented approaches, and symptomatic management of neuropathic pain. Various mono- and combination pharmacotherapies as well as topical and neuromodulatory techniques are used to improve not only pain intensity but also sleep and quality of life.</p>

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Diabetische Polyneuropathie rechtzeitig erkennen und behandeln

  • 期刊论文

  • 发表日期：

    2026年1月7日

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  • Gidon J. Bönhof

摘要

Diabetic polyneuropathy is one of the most common chronic complications of diabetes with a major impact on mortality and quality of life, yet it remains a frequently overlooked and undertreated condition in clinical practice. It is typically characterized by a progressive distal to proximal loss of sensation in the lower extremity and, in around 50% of cases, with neuropathic symptoms in this area. A careful exclusion of other causes and efficient standardized clinical assessments aid in screening and a timely diagnosis. Strategies for prevention and treatment include the reduction of risk factors, pathogenetically-oriented approaches, and symptomatic management of neuropathic pain. Various mono- and combination pharmacotherapies as well as topical and neuromodulatory techniques are used to improve not only pain intensity but also sleep and quality of life.