Scholarlink

<p>The self-assembly of amphiphilic block copolymers (BCPs) in solutions supplies nanostructures with abundant morphologies, which are widely applied in drug delivery and bioimaging. However, electron microscopy (EM), a common evaluation method of morphologies, requires sophisticated instrumentation and sample pre-treatment. Simple and fast evaluation methods of morphologies in self-assembly were rarely presented. Herein, we synthesized polymer PEG-<i>b</i>-P(S-<i>co</i>-TVPA) (<b>PEG-PST</b>) composed of hydrophilic polyethylene glycol (PEG) and hydrophobic polystyrene (PS), where the latter was combined with solvent-responsive AIEgen named TVPA with twisted intramolecular charge transfer (TICT) effect. In a solution self-assembly system of <b>PEG-PST</b>, the morphology changed from spherical micelles to vesicles as size increased. This was primarily attributed to the hydrophobic interaction leading to the aggregation of PS, and the elongation of PS varied with the increase in precipitant (water) content. Additionally, the comparable solubility parameters between the solvent and PS, along with the inferior solubility of <b>PEG-PST</b>, further promoted the alteration of morphology. Meanwhile, with increasing solution polarity, the emission color change from blue to red was caused by the TICT effect and confinement of TVPA within PS. The relation between morphologies and colors realized intuitive distinguishment of morphologies through variation of colors.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Visualization of different morphologies of block copolymer assemblies using various fluorescent colors via the introduction of solvent-responsive AIEgen

  • 期刊论文

  • 发表日期：

    2025年4月23日

查看全文
  • Shaoyu Xu,
  • Mian Wang,
  • Hui Liu,
  • Jinsa Li,
  • Renhua Deng,
  • Xiaofan Ji

摘要

The self-assembly of amphiphilic block copolymers (BCPs) in solutions supplies nanostructures with abundant morphologies, which are widely applied in drug delivery and bioimaging. However, electron microscopy (EM), a common evaluation method of morphologies, requires sophisticated instrumentation and sample pre-treatment. Simple and fast evaluation methods of morphologies in self-assembly were rarely presented. Herein, we synthesized polymer PEG-b-P(S-co-TVPA) (PEG-PST) composed of hydrophilic polyethylene glycol (PEG) and hydrophobic polystyrene (PS), where the latter was combined with solvent-responsive AIEgen named TVPA with twisted intramolecular charge transfer (TICT) effect. In a solution self-assembly system of PEG-PST, the morphology changed from spherical micelles to vesicles as size increased. This was primarily attributed to the hydrophobic interaction leading to the aggregation of PS, and the elongation of PS varied with the increase in precipitant (water) content. Additionally, the comparable solubility parameters between the solvent and PS, along with the inferior solubility of PEG-PST, further promoted the alteration of morphology. Meanwhile, with increasing solution polarity, the emission color change from blue to red was caused by the TICT effect and confinement of TVPA within PS. The relation between morphologies and colors realized intuitive distinguishment of morphologies through variation of colors.