<p>Population aging requires innovative technological strategies that promote autonomy, functionality, and well-being in old age. In this context, mixed reality (MR), a technology that integrates physical and digital elements in a shared and interactive real-time environment, emerges as a promising alternative. To analyze the current state of evidence on the use of MR in the care of older adults, including its theoretical and practical implications. Scientific articles were reviewed in Scopus, Web of Science, PubMed, IEEE Xplore, and EBSCO. Data from 15 studies were organized into an analytical matrix to identify methodological and impact patterns. MR interventions have shown promising preliminary results in physical rehabilitation, cognitive stimulation, emotional well-being, and social interaction by combining sensory feedback, functional tasks, and meaningful experiences. The included studies represent heterogeneous MR configurations along the virtual reality continuum, including transparent or pass-through optical viewers, VR-HMD-based systems with real-world interaction, and sensor- or projection-based platforms. Rather than demonstrating superiority over virtual or augmented reality, the evidence suggests specific advantages related to contextual awareness, physical interaction, and cognitive-motor-affective integration. These features were associated with potential improvements in mobility, executive functions, motivation, positive emotions, and social presence, supporting an interpretive cognitive-motor-emotional framework and the design of safe, meaningful, and context-sensitive interventions. MR shows promising potential for the care of older adults by improving cognitive, motor, emotional, and social outcomes. However, current evidence remains preliminary due to small sample sizes, methodological heterogeneity, a scarcity of comparative studies, and a lack of longitudinal evidence.</p>