Background <p>Research evidence suggests that mouth rinsing (MR) has an ergogenic potential. However, recent systematic reviews have been limited to studies that predominantly included individual athletes and analyzed parameters that are not sport-specific for team sports. The aim of this review is to evaluate the effectiveness of different MR strategies specifically in the context of team sports.</p> Methods <p>A systematic review was conducted according to the PRISMA guidelines with pre-defined PICOS criteria. Publication search was performed in the Cochrane Library, PubMed, and Mendeley databases since the inception till February 2025.The study quality was assessed using the Cochrane risk-of-bias tool for randomized trials (RoB2).</p> Results <p>Fifteen studies involving 246 team sport athletes, all with low risk of bias, met the inclusion criteria. CHO MR (<i>n</i> = 11) was the most studied, followed by CHO + CAF MR (<i>n</i> = 3), CAF MR (<i>n</i> = 2), MEN MR (<i>n</i> = 2), and CAP MR (<i>n</i> = 1). The key outcomes included speed-strength, external/internal load, repeated sprint ability, endurance, perceptual skills, and thermal sensation. The majority of studies (6 out of 11) failed to demonstrate evidence of positive effects from CHO MR on the analyzed key outcomes. In contrast, the use of CAF MR at relatively high doses may exert beneficial influences on endurance, strength, and reaction time. Meanwhile, evidence for MEN MR is limited to isolated studies showing efficacy solely in thermal sensation, but not in physical performance. Notably, no adverse effects associated with the administration of these solutions were reported in any of the studies.</p> Conclusions <p>The obtained data do not provide convincing evidence supporting the positive impact of mouth rinses with various flavors on physical performance in team sport athletes. However, the application of these rinses is safe, representing a critical factor for their practical implementation.</p>