Background <p>The evidence about the effects of exercise training on flow-mediated dilation is inconsistent in people with coronary heart disease. This study aimed to analyze the effects of exercise training on flow-mediated dilation in individuals with coronary heart disease by synthesizing the published literatures.</p> Methods <p>We systematically searched the following databases up to March 2025: PubMed, Web of Science, Embase, and the Cochrane Library. Randomized controlled trials evaluating exercise interventions on flow-mediated dilation in people with coronary heart disease were included. The standardized mean difference (SMD) with 95% confidence interval (CI) was calculated using a random-effects model.</p> Results <p>Six studies involving 985 participants were included. Our meta-analysis revealed a favorable effect on flow-mediated dilation for the exercise training group compared to the control group (SMD = 1.16, 95% CI 0.64 – 1.67). Subgroup analysis indicated positive effects on flow-mediated dilation for the aerobic training (SMD = 1.23, 95% CI 0.46 – 2.00) and combined training (SMD = 1.28, 95% CI 0.57 – 1.98) compared to the control group.</p> Conclusion <p>Exercise training, including both aerobic training and combined exercise training, may improve endothelial function in people with coronary heart disease.</p>