Scholarlink

Purpose <p>To identify polysomnographic predictors of adherence to positive airway pressure (PAP) therapy in adults with obstructive sleep apnea (OSA).</p> Methods <p>We performed a retrospective cohort study of adults with moderate to severe OSA who underwent full-night diagnostic polysomnography and initiated PAP therapy. Participants with previous PAP titration studies were excluded. Baseline demographic and polysomnographic variables were extracted, and adherence was defined as PAP use ≥ 4&#xa0;h/night on ≥ 70% of nights. Logistic regression identified factors independently associated with adherence.</p> Results <p>Among 100 enrolled patients, 61 met the adherence criteria. Compared with adherent patients, nonadherent patients did not differ in apnea–hypopnea index, oxygen desaturation index, lowest oxygen saturation, or low arousal threshold. Rapid eye movement–related OSA was significantly more prevalent in the nonadherent group and was the only independent predictor of nonadherence (adjusted odds ratio, 2.52; 95% confidence interval, 1.04–6.22; <i>p</i> = 0.033).</p> Conclusions <p>Rapid eye movement–related OSA was the only independent predictor of poor adherence to PAP therapy. Sleep stage–specific phenotyping may therefore assist in personalizing adherence-enhancing strategies. Prospective studies are warranted to validate these findings and evaluate targeted interventions.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Polysomnographic parameters predicting positive airway pressure adherence

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年11月10日

查看全文
  • Nattarin Nilrat,
  • Wish Banhiran,
  • Phawin Keskool,
  • Chawanont Pimolsri,
  • Navarat Kasemsuk

摘要

Purpose

To identify polysomnographic predictors of adherence to positive airway pressure (PAP) therapy in adults with obstructive sleep apnea (OSA).

Methods

We performed a retrospective cohort study of adults with moderate to severe OSA who underwent full-night diagnostic polysomnography and initiated PAP therapy. Participants with previous PAP titration studies were excluded. Baseline demographic and polysomnographic variables were extracted, and adherence was defined as PAP use ≥ 4 h/night on ≥ 70% of nights. Logistic regression identified factors independently associated with adherence.

Results

Among 100 enrolled patients, 61 met the adherence criteria. Compared with adherent patients, nonadherent patients did not differ in apnea–hypopnea index, oxygen desaturation index, lowest oxygen saturation, or low arousal threshold. Rapid eye movement–related OSA was significantly more prevalent in the nonadherent group and was the only independent predictor of nonadherence (adjusted odds ratio, 2.52; 95% confidence interval, 1.04–6.22; p = 0.033).

Conclusions

Rapid eye movement–related OSA was the only independent predictor of poor adherence to PAP therapy. Sleep stage–specific phenotyping may therefore assist in personalizing adherence-enhancing strategies. Prospective studies are warranted to validate these findings and evaluate targeted interventions.