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<p>Obstructive Sleep Apnea (OSA) is the most common sleep- related breathing disorder. In recent years, evidence have shown that patients with OSA may have this disorder for different reasons, with different symptoms and comorbidities. Therefore, treatment should be individualized [<CitationRef CitationID="CR1">1</CitationRef>]. This has led to a growing interest in the characterization of the disease into phenotypes. OSA in elderly patients is often a challenge for clinician in terms of diagnosis, as symptoms may be masked, but also for treatment in terms of efficacy and adherence. However, aging is a pathophysiological factor that predisposes to obstructive sleep apnea, and the two conditions share symptoms and comorbidities to such an extent that it becomes very difficult to establish a casual link between the two. We summarize the recent evidence in OSA elderly patients, particularly in terms of pathophysiology, symptoms and main comorbidities.</p>

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Walking the fine line between OSA and aging

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年5月23日

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  • Caterina Antonaglia,
  • Antonio Fabozzi,
  • Alessia Steffanina,
  • Riccardo Ture,
  • Paolo Palange,
  • Marco Confalonieri

摘要

Obstructive Sleep Apnea (OSA) is the most common sleep- related breathing disorder. In recent years, evidence have shown that patients with OSA may have this disorder for different reasons, with different symptoms and comorbidities. Therefore, treatment should be individualized [1]. This has led to a growing interest in the characterization of the disease into phenotypes. OSA in elderly patients is often a challenge for clinician in terms of diagnosis, as symptoms may be masked, but also for treatment in terms of efficacy and adherence. However, aging is a pathophysiological factor that predisposes to obstructive sleep apnea, and the two conditions share symptoms and comorbidities to such an extent that it becomes very difficult to establish a casual link between the two. We summarize the recent evidence in OSA elderly patients, particularly in terms of pathophysiology, symptoms and main comorbidities.