<p>Selenium (Se) is an essential trace element that regulates bovine health and reproduction by being incorporated into selenoproteins involved in antioxidant defense, thyroid hormone metabolism, immune regulation, and redox homeostasis. This review synthesizes current evidence on the chemistry, bioavailability, metabolic fate, and reproductive functions of selenium in cattle. We emphasize the differences among inorganic, organic, and nano-selenium sources. Selenium status thresholds and supplementation strategies during critical physiological windows are summarized. We also highlight emerging insights linking selenium to ovarian function, uterine receptivity, embryonic survival, spermatogenesis, and peripartum health. Particular attention is given to selenium-mediated modulation of oxidative stress, inflammatory signaling pathways, and endocrine regulation. The review is based on a structured literature search of PubMed, Elsevier, Google Scholar, and other reputable databases. We focus on studies addressing selenium and cow reproduction, selenium sources, dairy cattle, and selenoproteins. Key knowledge gaps and future research priorities are highlighted to guide precision selenium nutrition in modern cattle systems.</p>

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Role of selenium in cow fertility and reproduction—A review

  • Samson O. Adeniran,
  • Silas O. Fagbenro,
  • Omowumi T. Kayode,
  • Agnieszka Partyka,
  • Heze Feng,
  • Peng Zheng

摘要

Selenium (Se) is an essential trace element that regulates bovine health and reproduction by being incorporated into selenoproteins involved in antioxidant defense, thyroid hormone metabolism, immune regulation, and redox homeostasis. This review synthesizes current evidence on the chemistry, bioavailability, metabolic fate, and reproductive functions of selenium in cattle. We emphasize the differences among inorganic, organic, and nano-selenium sources. Selenium status thresholds and supplementation strategies during critical physiological windows are summarized. We also highlight emerging insights linking selenium to ovarian function, uterine receptivity, embryonic survival, spermatogenesis, and peripartum health. Particular attention is given to selenium-mediated modulation of oxidative stress, inflammatory signaling pathways, and endocrine regulation. The review is based on a structured literature search of PubMed, Elsevier, Google Scholar, and other reputable databases. We focus on studies addressing selenium and cow reproduction, selenium sources, dairy cattle, and selenoproteins. Key knowledge gaps and future research priorities are highlighted to guide precision selenium nutrition in modern cattle systems.