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Purpose <p>Prostate cancer is a common malignancy in men, with radical prostatectomy (RP) being a major treatment option. This study investigates post-prostatectomy rehospitalisation rates and risk factors in a cohort of South Australian men who underwent RP from 2002 to 2021 (n = 5105).</p> Methods <p>Post-prostatectomy rehospitalisation rates at 30 and 90 days were measured from hospital discharge data, with reasons determined from ICD-10 codes. Rates per 1000 person-time were estimated, accounting for the length of follow-up. Zero inflated negative binomial regression analyses were used to identify sociodemographic and clinical factors associated with the number of hospital encounters following RP.</p> Results <p>Approximately 13% of patients had at least one hospital visit within 90 days post-prostatectomy. Common reasons for early rehospitalisation (within 30 days) were urinary obstruction (3.2%), haematuria (2.6%), and urinary tract infection (2.5%). Older age (aged 75 + vs &lt; 60: incidence rate ratio (IRR) 2.23, 95% CI: 1.88–2.64), highest comorbidity burden (3 + vs 0: IRR 2.33, 95% CI: 1.80–3.01), and high risk clinical characteristics (PSA &gt; 20 vs &lt; 10&#xa0;ng/mL: IRR 1.67, 95% CI: 1.34–2.08 and Gleason score 9–10 vs &lt; 7: IRR 1.39, 95% CI: 1.06–1.84) were associated with higher rehospitalisation rates. Conversely, men who were treated from 2016–2021 had 39% lower rehospitalisation rates (IRR 0.61, 95% CI: 0.53–0.71) compared with patients treated from 2002–2005.</p> Conclusion <p>These findings highlight the importance of considering patient characteristics and tailoring post-surgical care plans to minimise rehospitalisation. The reduction in rehospitalisation over time may reflect advancements in surgical techniques, better patient selection or improved surgeon experience.</p>

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Post-prostatectomy rehospitalisation rates and risk factors in South Australian men with prostate cancer: evidence from linked data

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月25日

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  • Tenaw Tiruye,
  • Alex Jay,
  • Michael O’Callaghan,
  • Liesel M. FitzGerald,
  • David Roder,
  • Kerri Beckmann

摘要

Purpose

Prostate cancer is a common malignancy in men, with radical prostatectomy (RP) being a major treatment option. This study investigates post-prostatectomy rehospitalisation rates and risk factors in a cohort of South Australian men who underwent RP from 2002 to 2021 (n = 5105).

Methods

Post-prostatectomy rehospitalisation rates at 30 and 90 days were measured from hospital discharge data, with reasons determined from ICD-10 codes. Rates per 1000 person-time were estimated, accounting for the length of follow-up. Zero inflated negative binomial regression analyses were used to identify sociodemographic and clinical factors associated with the number of hospital encounters following RP.

Results

Approximately 13% of patients had at least one hospital visit within 90 days post-prostatectomy. Common reasons for early rehospitalisation (within 30 days) were urinary obstruction (3.2%), haematuria (2.6%), and urinary tract infection (2.5%). Older age (aged 75 + vs < 60: incidence rate ratio (IRR) 2.23, 95% CI: 1.88–2.64), highest comorbidity burden (3 + vs 0: IRR 2.33, 95% CI: 1.80–3.01), and high risk clinical characteristics (PSA > 20 vs < 10 ng/mL: IRR 1.67, 95% CI: 1.34–2.08 and Gleason score 9–10 vs < 7: IRR 1.39, 95% CI: 1.06–1.84) were associated with higher rehospitalisation rates. Conversely, men who were treated from 2016–2021 had 39% lower rehospitalisation rates (IRR 0.61, 95% CI: 0.53–0.71) compared with patients treated from 2002–2005.

Conclusion

These findings highlight the importance of considering patient characteristics and tailoring post-surgical care plans to minimise rehospitalisation. The reduction in rehospitalisation over time may reflect advancements in surgical techniques, better patient selection or improved surgeon experience.