Scholarlink

<p>In the current situation, organic dyes are the potential candidates that contribute to pollution in water, and their degradation still poses a challenging question to scientists. Materials in the Nano-sized regime are attracting focused interest as they inherit enhanced features for their efficacy, feasibility, and go-green properties, initiating the drive for the present research. The present work focuses on the synthesis of ZnO nanoparticles using dill <i>(Anethum graveolens)</i> seed extract using an eco-friendly method. The obtained nanoparticles were analyzed using XRD, FT-IR, SEM, and EDX analysis to evaluate their structure, morphology, and phase composition. ZnO nanoparticles synthesized were employed for the catalytic reduction of dyes and anticancer activity. The nanoparticles displayed better catalytic activity, achieving the complete degradation of organic dyes, namely, methylene blue, congo red, 2-chloro-4-nitrophenol, and o-nitrobenzoic acid, within 10, 6, 12, and 15&#xa0;min, respectively, with a low catalyst loading of 2&#xa0;mg. This resulted in rate constants of 0.260, 0.237, 0.118, and 0.061&#xa0;min<sup>-1</sup>, with reduction efficiencies of 98%, 96%, 84%, and 90%, respectively, for each of the dyes. The reduced o-aminobenzoic acid from o-nitrobenzoic acid was isolated and confirmed by ¹H NMR spectroscopy. A good recovery yield was observed for the prepared materials, which maintained their catalytic activity over 5 cycles with a minimal decrease in performance. The ZnO nanoparticles also exhibited dose-dependent antiproliferative effects on human colon cancer cells, i.e., HCT116 cells, with an IC<sub>50</sub> of 12.07 <i>±</i> 0.53&#xa0;µg/mL, demonstrating significant anticancer effects.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Catalytic Reduction of Organic Pollutants and Anticancerous Activity of Eco-Friendly Synthesized ZnO Nanoparticles Using Dill Seed Extract

  • 期刊论文

  • 发表日期：

    2025年11月17日

查看全文
  • Guddappa Halligudra,
  • Chitrabanu C. Paramesh,
  • Amulya Giridasappa,
  • Chetana Sabbanahalli,
  • Kunal Roy,
  • Madhusudhana Ramanna,
  • Dinesh Rangappa,
  • Prasanna Daddakunche Shivaramu

摘要

In the current situation, organic dyes are the potential candidates that contribute to pollution in water, and their degradation still poses a challenging question to scientists. Materials in the Nano-sized regime are attracting focused interest as they inherit enhanced features for their efficacy, feasibility, and go-green properties, initiating the drive for the present research. The present work focuses on the synthesis of ZnO nanoparticles using dill (Anethum graveolens) seed extract using an eco-friendly method. The obtained nanoparticles were analyzed using XRD, FT-IR, SEM, and EDX analysis to evaluate their structure, morphology, and phase composition. ZnO nanoparticles synthesized were employed for the catalytic reduction of dyes and anticancer activity. The nanoparticles displayed better catalytic activity, achieving the complete degradation of organic dyes, namely, methylene blue, congo red, 2-chloro-4-nitrophenol, and o-nitrobenzoic acid, within 10, 6, 12, and 15 min, respectively, with a low catalyst loading of 2 mg. This resulted in rate constants of 0.260, 0.237, 0.118, and 0.061 min-1, with reduction efficiencies of 98%, 96%, 84%, and 90%, respectively, for each of the dyes. The reduced o-aminobenzoic acid from o-nitrobenzoic acid was isolated and confirmed by ¹H NMR spectroscopy. A good recovery yield was observed for the prepared materials, which maintained their catalytic activity over 5 cycles with a minimal decrease in performance. The ZnO nanoparticles also exhibited dose-dependent antiproliferative effects on human colon cancer cells, i.e., HCT116 cells, with an IC50 of 12.07 ± 0.53 µg/mL, demonstrating significant anticancer effects.

Graphical Abstract