<p>Sulfonamides and their derivatives are being used as potent chemosensors for various ions. Sensing ability of 4-methyl-N-(pyridin-2-yl) benzene-1-sulfonamide (S) was tested towards different cations i.e. Zn²⁺, Fe²⁺, Pb²⁺, Ni²⁺, Sr²⁺, Cd²⁺, Cu²⁺, Co²⁺, Hg²⁺ and Al³⁺ in Dimethyl Sulfoxide (DMSO). S exhibited sensitivity towards ferrous (Fe²⁺) and cupric (Cu²⁺) ions. Solution of S turned yellow from colorless upon interaction with iron and copper ions and a corresponding bathochromic shift was observed. Electronic spectra showed new absorbance peaks at 310&#xa0;nm and 370&#xa0;nm after interaction with Fe²⁺ and Cu²⁺ respectively, compared with S absorbance peak at 270&#xa0;nm. Binding studies indicated 1:1 binding stoichiometry of both metal ions with S. Detection limits for iron and copper were determined to be 0.74 µM and 0.60 µM, respectively. However, their binding constant values came out to be 1.3 × 10⁶ M⁻¹ and 1 × 10⁶ M⁻¹ respectively for Fe²⁺ and Cu²⁺.</p>