<p>Philodendrons are popular for their attractive foliage, diverse forms, and easy adaptability to indoor environments and play a vital role in the global ornamental plant industry. In vitro propagation techniques serve as excellent methods for the large-scale multiplication, conservation, and genetic enhancement of these vital species. This review explains the maintenance of aseptic conditions, shoot proliferation, root induction, and acclimatization strategies. To encourage shoot growth, the shoot of Philodendron species was cultured on Murashige and Skoog (MS) media containing different types and concentrations of plant growth regulators. In numerous studies, 6-benzylaminopurine (BAP) alone, from the group of cytokinin, found improved the shoot growth of Philodendron species. However, some studies have shown that using a combination of cytokinin and auxins can lead to a higher number of shoots. Among the tested auxins, indole-3-butyric acid (IBA) showed the best results for root induction in Philodendron species, resulting in the highest number of roots. In certain studies, 1-naphthaleneacetic acid (NAA) significantly increased the number of roots. Different planting substrates have been used to support the ex-vitro acclimatization of the plants. Peat moss and vermiculite showed a 100% survival rate, while perlite had a slightly lower survival rate (80%). Overall, the reviewed findings highlight the importance of optimizing PGR and acclimatization protocols to improve propagation efficiency. In vitro culture of Philodendron represents an effective strategy for large-scale commercial production.</p>