Mixed-precision arithmetic, widely adopted for performance, creates an overlooked opportunity for fault tolerance. Our mixed-precision panel factorization (MPF) algorithm already computes each LU panel in both FP16 and FP64 ; we show that this inherent redundancy enables soft-error detection at negligible additional cost. We propose four complementary detectors that compare checksum sketches of the two factorizations: Relative (thresholded checksum discrepancy), Ratio (outlier analysis of per-row differences), Hybrid (a randomized-probe combination of both with separate \(L\) - and \(U\) -factor checks), and CrossCheck (a lightweight cross-check inspired by algorithm-based fault tolerance). Experimental evaluation shows that Relative and CrossCheck achieve high sensitivity with low false-positive rates, while Hybrid maintains near-zero false positives with moderate sensitivity and complementary coverage for challenging significand-bit faults. Bit-level analysis confirms reliable detection of exponent- and sign-bit errors, with sensitivity decreasing gracefully for low-order significand bits whose perturbations approach the FP16 rounding floor. A lightweight panel-fingerprint mechanism extends protection beyond the factorization loop, closing the temporal gap before the triangular solve with guaranteed detection of any single-element corruption and zero false positives. The approach requires only linear work and constant storage per panel, preserving the cubic scaling of standard LU decomposition.