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<p>In this work, Schottky source/drain FinFET breast cancer cell detector is reported for the investigation of sensitivity and limit of detection (LoD) under microwave radiations of 900&#xa0;MHz and 10&#xa0;GHz. Schottky source/drain FinFET provides remarkable mechanical stability and biocompatibility to the Healthy/Malignant breast cells in its etched cavity. The MCF-10&#xa0;A (non-tumorigenic / healthy breast cell) and malignant breast cell (T-47D) exhibits unique dielectric properties under microwave radiations. These breast cells are electrically characterized through proposed breast cancer detector by measuring the variation in peak current with time corresponding to the particular radiation. The sensitivity analysis conducted on recommended detector has revealed that MCF-10&#xa0;A and T-47D offers sensitivity of 42.22% and 44.70% respectively under 900&#xa0;MHz radiation. Also, the recommended detector has exhibited better limit of detection of 0.234 and 0.309 for MCF-10&#xa0;A &amp; T-47D respectively. Moreover, investigation of Figure of merit (FOM) revealed that malignant breast cancerous cell (T-47D) offers superior sensing capability than MCF-10&#xa0;A. Our investigation showed that proposed breast cancer cell detector under the influence of 900&#xa0;MHz radiation exhibits higher sensitivity than 10&#xa0;GHz radiation. Channel material engineering of proposed detector revealed that GaAs offer higher sensitivity for MCF-10&#xa0;A and T-47D breast cells. It can be emphasized that proposed detector is a better candidate for the identification of healthy and cancerous breast cells.</p>

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Sensitivity and Limit of Detection (LoD) Analysis of Schottky Source/Drain FinFET Breast Cancer Cell Detector Under Microwave Radiation

  • 期刊论文

  • 发表日期：

    2025年7月30日

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  • Ronak Singh,
  • Yogesh Pratap,
  • Mridula Gupta

摘要

In this work, Schottky source/drain FinFET breast cancer cell detector is reported for the investigation of sensitivity and limit of detection (LoD) under microwave radiations of 900 MHz and 10 GHz. Schottky source/drain FinFET provides remarkable mechanical stability and biocompatibility to the Healthy/Malignant breast cells in its etched cavity. The MCF-10 A (non-tumorigenic / healthy breast cell) and malignant breast cell (T-47D) exhibits unique dielectric properties under microwave radiations. These breast cells are electrically characterized through proposed breast cancer detector by measuring the variation in peak current with time corresponding to the particular radiation. The sensitivity analysis conducted on recommended detector has revealed that MCF-10 A and T-47D offers sensitivity of 42.22% and 44.70% respectively under 900 MHz radiation. Also, the recommended detector has exhibited better limit of detection of 0.234 and 0.309 for MCF-10 A & T-47D respectively. Moreover, investigation of Figure of merit (FOM) revealed that malignant breast cancerous cell (T-47D) offers superior sensing capability than MCF-10 A. Our investigation showed that proposed breast cancer cell detector under the influence of 900 MHz radiation exhibits higher sensitivity than 10 GHz radiation. Channel material engineering of proposed detector revealed that GaAs offer higher sensitivity for MCF-10 A and T-47D breast cells. It can be emphasized that proposed detector is a better candidate for the identification of healthy and cancerous breast cells.