Recent advances in the development of biocompatible hybrid coatings on implant materials using plasma electrolytic oxidation
摘要
Plasma electrolytic oxidation (PEO) has long attracted the attention of researchers as an approach for the development of biocompatible layers on metallic medical implants. Due to the highly developed pore system of PEO coatings, various polymers can be introduced into their surface with the formation of hybrid structures that impart the desired bioactive properties to the implants. This review presents and summarizes the results of recent studies aimed at obtaining PEO-based biocompatible hybrid coatings. The principal methods for the preparation of such surfaces, as well as the materials used for their biofunctionalization, are described. A critical analysis of the existing approaches is carried out, and the advantages and disadvantages of the presented methods for forming surface layers not only on titanium, but also on magnesium implant materials are assessed.