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<p>Methyl analogs of lamellarins were synthesized in two steps <i>via</i> 1,3-dipolar cycloaddition of isoquinolinium ylides to nitrostyrenes ArCH=C(Me)NO<sub>2</sub> followed by lactone ring closure through <i>ortho</i>-MeO-substituent in the aryl fragment.</p>

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New synthetic approach to methyl analogs of lamellarins

  • 期刊论文

  • 发表日期：

    2025年12月1日

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  • N. A. Kuznetsov,
  • K. N. Alisultanov,
  • V. I. Ushkarov,
  • A. V. Samet,
  • V. V. Semenov

摘要

Methyl analogs of lamellarins were synthesized in two steps via 1,3-dipolar cycloaddition of isoquinolinium ylides to nitrostyrenes ArCH=C(Me)NO2 followed by lactone ring closure through ortho-MeO-substituent in the aryl fragment.