<p>This review covers experimental data acquired on the interconversion of two forms of nitric oxide (NO) that is a universal regulator in biological processes: dinitrosyl iron complexes (DNICs) containing thiol ligands and S-nitrosothiols (RS—NO). This inter-conversion may lead to the occurrence of self-sustaining chemical system in living organisms, maintaining the transportation of DNICs, RS—NO, NO, and NO<sup>+</sup> in cells and tissues in an autowave mode. Concepts from a novel branch of chemistry, <i>viz</i>. the spin chemistry, one among the founders of which is Academician A. L. Buchachenko, were used herein.</p>

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The nature of depots for nitric oxide in living organisms

  • A. F. Vanin

摘要

This review covers experimental data acquired on the interconversion of two forms of nitric oxide (NO) that is a universal regulator in biological processes: dinitrosyl iron complexes (DNICs) containing thiol ligands and S-nitrosothiols (RS—NO). This inter-conversion may lead to the occurrence of self-sustaining chemical system in living organisms, maintaining the transportation of DNICs, RS—NO, NO, and NO+ in cells and tissues in an autowave mode. Concepts from a novel branch of chemistry, viz. the spin chemistry, one among the founders of which is Academician A. L. Buchachenko, were used herein.