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<p>A selective one-pot synthesis of substituted 2-(dimethylaminomethyl)phenols has been developed, affording yields of 90–98%. The method is based on the reaction of phenols with bis(dimethylamino)methane, catalyzed by copper(<span>i</span>) salts immobilized on SiO<sub>2</sub> and Al<sub>2</sub>O<sub>3</sub></p>

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Copper salts immobilized on SiO2 and Al2O3 as effective catalysts for aminomethylation of phenols

  • 期刊论文

  • 发表日期：

    2025年7月1日

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  • M. G. Shaibakova,
  • L. K. Dilmukhametova,
  • I. R. Ramazanov

摘要

A selective one-pot synthesis of substituted 2-(dimethylaminomethyl)phenols has been developed, affording yields of 90–98%. The method is based on the reaction of phenols with bis(dimethylamino)methane, catalyzed by copper(i) salts immobilized on SiO2 and Al2O3