<p>Calcium ferrites (CaFe₂O₄) have emerged as a promising class of materials due to their unique properties, including high chemical stability, eco-friendliness, and biocompatibility. This review thoroughly examines recent developments in the synthesis and uses of nanomaterials based on CaFe₂O₄, with an emphasis on their use in energy storage, medicinal sectors, environmental remediation, and heterogeneous catalysis. It is examined how well CaFe₂O₄ performs in supercapacitors and battery technologies, as well as its catalytic efficiency in a variety of organic transformations and pest destruction. Additionally, a critical evaluation is conducted on the potential of calcium ferrite in drug delivery, antibacterial, and hyperthermia applications. Even with its potential, problems like poor electrical conductivity and scalability still exist. Additionally, these limitations are discussed in this review along with potential future strategies for improving the performance of calcium ferrite-based systems. The goal of this work is to serve as a useful resource for researchers looking to develop effective and sustainable nanomaterial-based solutions by highlighting the numerous uses and enduring difficulties.</p>