In this paper, we deal with a lowering operator, denoted by \(\Lambda _{k, l}^{\varvec{\theta }, \varvec{q}, \varvec{a}, \varvec{b}},\) defined as a finite product of lowering operators in terms of the q-Dunkl operator. Our first goal is to characterize polynomial sequences that satisfy an Appell relation with respect to such an operator. Second, taking into account a cubic decomposition of a q-Dunkl–Appell sequence, we prove that sequences of their polynomial components exhibit \(\Lambda _{k, l}^{\varvec{\theta }, \varvec{q}, \varvec{a}, \varvec{b}}\) -Appell properties, but expressed through a product of three operators related to the q-Dunkl operator. Generating functions of the principal components in the cubic decomposition of a q-Dunkl–Appell monic polynomial sequence are deduced.