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Purpose <p>Many studies have demonstrated that chronic pain negatively impacts quality of life (QoL). However, it remains uncertain whether an individual’s QoL prior to an episode of acute pain is associated with an increased risk of chronic pain-related disability.<!--Query ID="Q1" Text="Journal instruction requires a city and country for affiliations; however, these are missing in affiliations. Please verify if the provided city and country are correct and amend if necessary." Resolved="yes"--> Our objective was to determine if an individual’s QoL prior to an acute painful event is associated with significant chronic pain-related disability following an emergency visit for acute pain.<!--Query ID="Q2" Text="Please check and confirm that the authors and their respective affiliations have been correctly identified and amend if necessary." Resolved="yes"--></p> Methods <p>This was a planned sub-study on a prospective cohort with a 3&#xa0;month follow-up. The primary outcome was defined as at least a moderate disability on the Pain Disability Index. QoL was assessed using the Short Form-12 Health Survey, which consists of 12 questions grouped into eight subscales, each ranging from 0 to 100. These subscales are divided into four physical factors and four mental factors, with lower scores representing worse quality of health. We used a multivariable logistic regression to assess the association between pre-event QoL and at least moderate chronic pain-related disability.</p> Results <p>A total of 1493 patients were included (mean age: 52&#xa0;years [SD ± 16]; female: 53%). After multivariable analysis, poorer physical factors (AOR = 1.53; 95% CI 1.22–1.93) and poorer mental factors (AOR = 1.22; 95% CI 1.02–1.46) were independently associated with at least moderate chronic pain-related disability.</p> Conclusions <p>Patients with poorer QoL prior to experiencing acute pain are more likely to develop significant chronic pain-related disability. This could help identify patients at higher risk, enabling the implementation of preventive strategies aimed at improving overall prognosis.</p>

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Association between quality of life before an acute pain event and the development of chronic pain-related disability

  • 期刊论文

  • 发表日期：

    2025年12月29日

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  • Alexandra Beaudin,
  • Raoul Daoust,
  • Jean Paquet,
  • Justin W. Yan,
  • David Williamson,
  • Jeffrey J. Perry,
  • Vérilibe Huard,
  • Eddy Lang,
  • Clémence Bossard,
  • Alexis Cournoyer

摘要

Purpose

Many studies have demonstrated that chronic pain negatively impacts quality of life (QoL). However, it remains uncertain whether an individual’s QoL prior to an episode of acute pain is associated with an increased risk of chronic pain-related disability. Our objective was to determine if an individual’s QoL prior to an acute painful event is associated with significant chronic pain-related disability following an emergency visit for acute pain.

Methods

This was a planned sub-study on a prospective cohort with a 3 month follow-up. The primary outcome was defined as at least a moderate disability on the Pain Disability Index. QoL was assessed using the Short Form-12 Health Survey, which consists of 12 questions grouped into eight subscales, each ranging from 0 to 100. These subscales are divided into four physical factors and four mental factors, with lower scores representing worse quality of health. We used a multivariable logistic regression to assess the association between pre-event QoL and at least moderate chronic pain-related disability.

Results

A total of 1493 patients were included (mean age: 52 years [SD ± 16]; female: 53%). After multivariable analysis, poorer physical factors (AOR = 1.53; 95% CI 1.22–1.93) and poorer mental factors (AOR = 1.22; 95% CI 1.02–1.46) were independently associated with at least moderate chronic pain-related disability.

Conclusions

Patients with poorer QoL prior to experiencing acute pain are more likely to develop significant chronic pain-related disability. This could help identify patients at higher risk, enabling the implementation of preventive strategies aimed at improving overall prognosis.