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<p>Originating in North America, the plant genus Ambrosia has become a very significant invasive species globally, capable of producing vast quantities of highly allergenic pollen. The genus includes around 50 species and poses considerable health risks due its pollen which is a major cause of allergic rhinitis. The chemical constituents of Ambrosia, commonly known as ragweed, was studied revealing 295 compounds. The diverse constituents predominantly include sesquiterpenoids, flavonoids, terpenoids, steroids, and coumarins. Plant species of this genus exhibit a wide range of biological activities, including molluscicidal, antitumor, antimycobacterial, antiproliferative, antioxidant, antiherbivore, and allelopathic properties. Medicinally, various Ambrosia species have demonstrated antibacterial, hypoglycemic, and other therapeutic properties, with specific extracts showing promising results against multiple bacterial and fungal strains. <i>Ambrosia artemisiifolia</i>, <i>Ambrosia trifida</i>, and <i>Ambrosia maritima</i> dominate the Ambrosia genus. This comprehensive review highlights the importance of understanding the chemical and biological diversity within the genus Ambrosia, given its significant health implications and potential therapeutic applications.</p>

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A comprehensive review of secondary metabolites of the plant genus Ambrosia

  • 期刊论文

  • 发表日期：

    2025年7月14日

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  • Shravan Kumar Gunda,
  • Venkata Aditya Duvvuri,
  • Ramya Cheriyala

摘要

Originating in North America, the plant genus Ambrosia has become a very significant invasive species globally, capable of producing vast quantities of highly allergenic pollen. The genus includes around 50 species and poses considerable health risks due its pollen which is a major cause of allergic rhinitis. The chemical constituents of Ambrosia, commonly known as ragweed, was studied revealing 295 compounds. The diverse constituents predominantly include sesquiterpenoids, flavonoids, terpenoids, steroids, and coumarins. Plant species of this genus exhibit a wide range of biological activities, including molluscicidal, antitumor, antimycobacterial, antiproliferative, antioxidant, antiherbivore, and allelopathic properties. Medicinally, various Ambrosia species have demonstrated antibacterial, hypoglycemic, and other therapeutic properties, with specific extracts showing promising results against multiple bacterial and fungal strains. Ambrosia artemisiifolia, Ambrosia trifida, and Ambrosia maritima dominate the Ambrosia genus. This comprehensive review highlights the importance of understanding the chemical and biological diversity within the genus Ambrosia, given its significant health implications and potential therapeutic applications.