<p>The process of preparing bismuth tripotassium dicitrate, which is used as an active pharmaceutical ingredient in the production of antiulcer drugs, from high-purity bismuth citrate and high-purity metallic bismuth was studied. It was shown that high-purity bismuth-potassium-ammonium citrate could be obtained from bismuth citrate by adding it to a solution of potassium citrate together with KOH, bringing the pH of the solution to 8 – 9 by adding an aqueous solution of ammonia, and crystallizing the product by evaporation of the solution at 60 – 70°C or spray drying at 230°C. Based on the conducted studies, the possibility of preparing bismuth tripotassium dicitrate from technical-grade metallic bismuth by oxidizing it with atmospheric oxygen, dissolving the resulting bismuth oxide in nitric acid (6 M), purifying the resulting bismuth-containing solution from metal impurities by precipitating bismuth as the oxohydroxynitrate of composition [Bi₆O₄(OH)₄](NO₃)₆·H₂O with its subsequent conversion to the citrate of composition BiC₆H₅O₇, dissolving the resulting citrate in an aqueous solution of KOH in the presence of ammonium hydroxide, and crystallizing the product was demonstrated.</p>