<p>Societal uncertainty is driving rising levels of anxiety within religious communities, often mirroring the acute distress observed in healthcare and trauma-related settings. While anxiety is commonly addressed as a psychological symptom, this article approaches anxiety as a complex, multilayered experience shaped by neurobiological threat responses, existential concerns regarding finitude and control, and spiritually meaningful struggles. Drawing on contemporary neuroscience, psychology of religion, and pastoral theology, this article presents an integrative framework for pastoral care that bridges clinical and congregational contexts. Anxiety is understood as a form of existential disorientation—what Kierkegaard (1844/1980) described as the “dizziness of freedom”—emerging when established orienting systems collapse under conditions of threat or uncertainty. Clinical chaplaincy practices, especially interventions that facilitate movement from defensive survival states toward the window of tolerance through regulation, lament, and spiritual reappraisal, are examined as models for pastoral leadership. This article argues that reframing anxiety as neither a failure of faith nor a purely pathological condition allows caregivers to support adaptive meaning-making, relational trust, and spiritual integration. Implications are discussed for pastoral caregivers, chaplains, and clinicians working at the intersection of psychology, spirituality, and care.</p>