Scholarlink

<p>Leptospirosis, a neglected tropical zoonotic disease of emerging concern, poses a significant public health threat, particularly in regions vulnerable to heavy rainfall and flooding. This study investigates the dynamics of leptospirosis by employing a comprehensive mathematical model incorporating the temperature-dependent square root growth rate of <i>Leptospira</i>, the causative bacteria. Delving into intricate transmission dynamics, we conduct a stability analysis, identify transcritical bifurcation, and estimate parameters, including the sensitivity index of the reproduction number. Numerical results demonstrate the theoretical results, underscoring the substantial influence of rainfall, climate, and agriculture on leptospirosis prevalence in tropical India, with specific predictions for cases in Kerala and Ratnagiri. In conclusion, our study urges urgent preventive measures, including enhanced surveillance, impactful awareness campaigns, targeted interventions, and improved hygiene practices, which are necessary to curb leptospirosis and improve public health in India.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Understanding the dynamics and drivers of leptospirosis in tropical and subtropical regions: a mathematical and epidemiological approach

  • 期刊论文

  • 发表日期：

    2025年1月2日

查看全文
  • Antima,
  • Sandip Banerjee

摘要

Leptospirosis, a neglected tropical zoonotic disease of emerging concern, poses a significant public health threat, particularly in regions vulnerable to heavy rainfall and flooding. This study investigates the dynamics of leptospirosis by employing a comprehensive mathematical model incorporating the temperature-dependent square root growth rate of Leptospira, the causative bacteria. Delving into intricate transmission dynamics, we conduct a stability analysis, identify transcritical bifurcation, and estimate parameters, including the sensitivity index of the reproduction number. Numerical results demonstrate the theoretical results, underscoring the substantial influence of rainfall, climate, and agriculture on leptospirosis prevalence in tropical India, with specific predictions for cases in Kerala and Ratnagiri. In conclusion, our study urges urgent preventive measures, including enhanced surveillance, impactful awareness campaigns, targeted interventions, and improved hygiene practices, which are necessary to curb leptospirosis and improve public health in India.