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Purpose <p>To systematically review the existent data on disease-specific quality of life (QOL) measures for sporadic vestibular schwannoma (VS), with a specific focus on comparing QOL outcomes among observation, radiosurgery, and microsurgery.</p> Methods <p>Systematic review.</p> Results <p>A systematic review identified 751 unique publications on QOL in VS, with a total of 39 articles reporting disease-specific measures of QOL. Of these, 26 articles evaluated QOL of VS patients after management, including 14 that compared QOL metrics among observation, radiosurgery, and microsurgery. When comparing these three primary treatment modalities for VS, nine of the 14 articles did not demonstrate clinically significant differences in QOL scores among treatment types. There were no consistent trends among the publications to help guide selection of treatment modality based on QOL scores.</p> Conclusion <p>While disease-specific tools exist for quantifying QOL in VS, to date, no consistent, clinically significant differences in QOL have been reported among management strategies for patients with sporadic VS.</p>

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Systematic review of disease-specific quality of life in patients with sporadic vestibular schwannoma

  • 期刊论文

  • 发表日期：

    2025年12月24日

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  • Karl R. Khandalavala,
  • Nader G. Zalaquett,
  • Christine M. Lohse,
  • Michael J. Link,
  • Matthew L. Carlson

摘要

Purpose

To systematically review the existent data on disease-specific quality of life (QOL) measures for sporadic vestibular schwannoma (VS), with a specific focus on comparing QOL outcomes among observation, radiosurgery, and microsurgery.

Methods

Systematic review.

Results

A systematic review identified 751 unique publications on QOL in VS, with a total of 39 articles reporting disease-specific measures of QOL. Of these, 26 articles evaluated QOL of VS patients after management, including 14 that compared QOL metrics among observation, radiosurgery, and microsurgery. When comparing these three primary treatment modalities for VS, nine of the 14 articles did not demonstrate clinically significant differences in QOL scores among treatment types. There were no consistent trends among the publications to help guide selection of treatment modality based on QOL scores.

Conclusion

While disease-specific tools exist for quantifying QOL in VS, to date, no consistent, clinically significant differences in QOL have been reported among management strategies for patients with sporadic VS.