Accuracy of intra-operative brain tumor squash cytology compared to large excision biopsy: a comparative study at the University Teaching Hospital of Kigali (CHUK), Rwanda
摘要
Accurate brain tumor diagnosis guides effective management, with large excision biopsy as the gold standard. Intra-operative cytologic smear techniques offer rapid analysis, particularly useful in resource-limited settings. The aim of this study was to evaluate the diagnostic accuracy and clinical utility of intra-operative cytologic smear techniques in brain tumor surgery at the University Teaching Hospital of Kigali (CHUK).
ObjectivesTo evaluate the diagnostic accuracy and clinical utility of intra-operative cytologic smear compared to large excision biopsy in brain tumor surgery at CHUK.
MethodsA prospective cross-sectional study involving 77 patients with radiologically confirmed brain tumors undergoing surgery at CHUK. Squash cytology diagnoses were compared with final histopathology diagnoses for concordance.
ResultsSquash cytology showed 89.6% agreement with histopathology. Major tumor types such as gliomas and meningiomas were reliably identified, facilitating timely surgical decisions.
ConclusionsIntra-operative squash cytology is a rapid and reliable adjunct to large biopsy, improving brain tumor management in low-resource settings. Integration of advanced techniques could enhance diagnostic precision further.