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<p><b>Objective.</b> To analyze the sex and age characteristics of modifiable risk factors for stroke in patients with type 2 diabetes mellitus (DM2). <b>Materials and methods.</b> This single-center study included 476 patients with DM2, with an average age of 58 [36; 79] years. Patients were divided into groups by sex and age. Clinical, history, and laboratory parameters, as well as modifiable stroke risk factors, were assessed. The presence of polyneuropathy was assessed in all patients. <b>Results.</b> The most common risk factors for stroke among all patients with DM2 were hyperglycemia (60.9%), arterial hypertension (HTN, 59.8%), tachycardia (57.7%), proteinuria (57.3%), chronic renal failure (CRF, 49.5%), hypercholesterolemia (HCH, 47.2%), overweight (OW, 43.6%), anemia (35.0%), and obesity (31.7%). The frequencies of anemia, hyperglycemia, and CRF were higher in women than in men. Polyneuropathy was more common in men (36.2 and 14.8%, <i>p</i> &lt; 0.05). Hyperglycemia was more common in young patients of both sexes. HTN, hyperglycemia, and tachycardia were prevalent in both men and women aged 45–59 years. In elderly men, the main risk factors were HTN (50%), CRF (51.6%), and tachycardia (48.3%), while the main risk factors in women were hyperglycemia (63.0%), CRF (63.0%), and HTN (60.5%). In the old, hyperglycemia (72.7%), HTN (63.6%), and OW (54.5%) predominated in women. Correlation analysis showed a direct relationship between venous blood glucose levels and heart rate, systolic, diastolic, and mean arterial pressure (BP), as well as an inverse relationship with hemoglobin levels and glomerular filtration rate. In men, glucose levels also correlated with pulse pressure and proteinuria. <b>Conclusion.</b> The results obtained here emphasize the importance of strengthening the control of glucose and BP, especially in young patients.</p>

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Sex and Age Characteristics of Risk Factors for Stroke in Patients with Type 2 Diabetes Mellitus

  • 期刊论文

  • 发表日期：

    2026年2月24日

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  • I. T. Murkamilov,
  • K. A. Aitbaev,
  • V. V. Fomin,
  • F. A. Yusupov,
  • Z. F. Yusupova,
  • T. F. Yusupova,
  • Zh. I. Solizhonov,
  • I. R. Boymurodov

摘要

Objective. To analyze the sex and age characteristics of modifiable risk factors for stroke in patients with type 2 diabetes mellitus (DM2). Materials and methods. This single-center study included 476 patients with DM2, with an average age of 58 [36; 79] years. Patients were divided into groups by sex and age. Clinical, history, and laboratory parameters, as well as modifiable stroke risk factors, were assessed. The presence of polyneuropathy was assessed in all patients. Results. The most common risk factors for stroke among all patients with DM2 were hyperglycemia (60.9%), arterial hypertension (HTN, 59.8%), tachycardia (57.7%), proteinuria (57.3%), chronic renal failure (CRF, 49.5%), hypercholesterolemia (HCH, 47.2%), overweight (OW, 43.6%), anemia (35.0%), and obesity (31.7%). The frequencies of anemia, hyperglycemia, and CRF were higher in women than in men. Polyneuropathy was more common in men (36.2 and 14.8%, p < 0.05). Hyperglycemia was more common in young patients of both sexes. HTN, hyperglycemia, and tachycardia were prevalent in both men and women aged 45–59 years. In elderly men, the main risk factors were HTN (50%), CRF (51.6%), and tachycardia (48.3%), while the main risk factors in women were hyperglycemia (63.0%), CRF (63.0%), and HTN (60.5%). In the old, hyperglycemia (72.7%), HTN (63.6%), and OW (54.5%) predominated in women. Correlation analysis showed a direct relationship between venous blood glucose levels and heart rate, systolic, diastolic, and mean arterial pressure (BP), as well as an inverse relationship with hemoglobin levels and glomerular filtration rate. In men, glucose levels also correlated with pulse pressure and proteinuria. Conclusion. The results obtained here emphasize the importance of strengthening the control of glucose and BP, especially in young patients.