Scholarlink

<p>Red-emissive nanoprobes for bioimaging are often limited by low quantum yields and poor aqueous stability. We developed carbon dots via hydrothermal condensation of citric acid and formamide with hydroxyethylidene diphosphonic acid and polyol coprecursors, followed by cationic surfactant (Berol™ 561) functionalization. The resulting carbon dots exhibit bright red photoluminescence (585–640&#xa0;nm) with quantum yields of 14–20% in water which were retained for over 2&#xa0;weeks. They show negligible cytotoxicity across HeLa, 4T1, and H9c2 cell lines at concentrations up to 100&#xa0;µg /mL. This surfactant-mediated surface engineering strategy yields stable, biocompatible carbon dots suitable for in vitro and in vivo bioimaging.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Bright and stable aqueous red-emissive carbon dots based on citric acid and formamide via surfactant treatment

  • 期刊论文

  • 发表日期：

    2026年2月28日

查看全文
  • Igor G. Spiridonov,
  • Aleksandra V. Koroleva,
  • Evgenii V. Zhizhin,
  • Yingqi Liang,
  • Songnan Qu,
  • Sergei A. Cherevkov,
  • Elena V. Ushakova

摘要

Red-emissive nanoprobes for bioimaging are often limited by low quantum yields and poor aqueous stability. We developed carbon dots via hydrothermal condensation of citric acid and formamide with hydroxyethylidene diphosphonic acid and polyol coprecursors, followed by cationic surfactant (Berol™ 561) functionalization. The resulting carbon dots exhibit bright red photoluminescence (585–640 nm) with quantum yields of 14–20% in water which were retained for over 2 weeks. They show negligible cytotoxicity across HeLa, 4T1, and H9c2 cell lines at concentrations up to 100 µg /mL. This surfactant-mediated surface engineering strategy yields stable, biocompatible carbon dots suitable for in vitro and in vivo bioimaging.