Scholarlink

Purpose <p>This study aimed to evaluate the antioxidative effects of methanolic and aqueous extracts of <i>Dalbergia sissoo</i> and <i>Aegle marmelos</i> on the oxidative stress index (OSI) in diarrheic calves affected by colibacillosis in the Bikaner region of Rajasthan, India.</p> Methods <p>A total of 32 colibacillosis-infected calves were randomly assigned to four treatment groups (<i>n</i> = 8 per group) to assess the efficacy of different extract-based regimens. The experimental groups received either methanolic or aqueous extracts of <i>Aegle marmelos</i> unripe fruit (150&#xa0;mg/kg body weight, twice daily for five days) or <i>Dalbergia sissoo</i> leaves (1000&#xa0;mg/kg body weight, twice daily for five days). Additionally, eight clinically healthy calves served as a control group. Polymerase chain reaction (PCR) analysis was performed to confirm colibacillosis. Statistical analysis revealed a significant reduction (<i>p</i> &lt;.05) in OSI values between pre-treatment and post-treatment (days 3 and 6) and across all treatment groups over time.</p> Results <p>The findings of this study indicate that methanolic and aqueous extracts of <i>Dalbergia sissoo</i> and <i>Aegle marmelos</i> exhibit potent antioxidative properties. These extracts significantly reduce oxidative stress in colibacillosis-affected calves.</p> Conclusion <p>The observed antioxidative effects suggest that <i>Dalbergia sissoo</i> and <i>Aegle marmelos</i> extracts may serve as potential natural therapeutic agents for managing oxidative stress in diarrheic calves.</p> Clinical trial number <p>40 under trial registration no CVAS/IAEC/CPCSEA-2044/GO/Re/SL/18/2021-22/11/40 for year 2021–2022.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Anti-oxidative activities of Dalbergia sissoo and Aegle marmelos extracts in calves with colibacillosis inhabiting the tropical desert climatic region of Rajasthan (India)

  • 期刊论文

  • 发表日期：

    2025年4月7日

查看全文
  • T. C. Nayak,
  • A. P. Singh,
  • Pooja Solanki,
  • J. P. Kachhawa,
  • S. R. Gupta

摘要

Purpose

This study aimed to evaluate the antioxidative effects of methanolic and aqueous extracts of Dalbergia sissoo and Aegle marmelos on the oxidative stress index (OSI) in diarrheic calves affected by colibacillosis in the Bikaner region of Rajasthan, India.

Methods

A total of 32 colibacillosis-infected calves were randomly assigned to four treatment groups (n = 8 per group) to assess the efficacy of different extract-based regimens. The experimental groups received either methanolic or aqueous extracts of Aegle marmelos unripe fruit (150 mg/kg body weight, twice daily for five days) or Dalbergia sissoo leaves (1000 mg/kg body weight, twice daily for five days). Additionally, eight clinically healthy calves served as a control group. Polymerase chain reaction (PCR) analysis was performed to confirm colibacillosis. Statistical analysis revealed a significant reduction (p <.05) in OSI values between pre-treatment and post-treatment (days 3 and 6) and across all treatment groups over time.

Results

The findings of this study indicate that methanolic and aqueous extracts of Dalbergia sissoo and Aegle marmelos exhibit potent antioxidative properties. These extracts significantly reduce oxidative stress in colibacillosis-affected calves.

Conclusion

The observed antioxidative effects suggest that Dalbergia sissoo and Aegle marmelos extracts may serve as potential natural therapeutic agents for managing oxidative stress in diarrheic calves.

Clinical trial number

40 under trial registration no CVAS/IAEC/CPCSEA-2044/GO/Re/SL/18/2021-22/11/40 for year 2021–2022.