Obtaining of biosoluble magnesium-based materials by powder metallurgy methods (a review)
摘要
A multifactorial analysis of the challenges associated with ensuring optimal characteristics of studied materials, including mechanical properties, biocompatibility, and controlled degradation rates, was carried out. The structural features of magnesium alloys and their alloying methods, which influence the final material properties, are discussed. A review is provided on calcium, zinc, aluminum, lithium, and rare-earth metals influence on corrosion resistance, mechanical strength, and regulated biodegradability. The technological aspects of magnesium biomaterial manufacturing, including casting, powder metallurgy, thermomechanical treatment, and biocompatible coating application, are analyzed. Particular attention is paid to the influence of magnesium alloys’ microstructure on their behavior in biological environments. The physicochemical processes occurring during material dissolution are investigated, and the influence of corrosion products on surrounding tissues is evaluated. A review of current research on the development of biodegradable magnesium-based materials, which have found widespread application in the biomedical field, particularly for the production of temporary implants, is presented. It is established that magnesium alloys, especially those with rare-earth element additives obtained by powder metallurgy methods, are prospective.