Objective <p>To pilot test the initial efficacy of the Baby-Feed website for improving infant diet quality (main outcome) and weight gain (exploratory outcome) compared to usual care.</p> Methods <p>This was a 3-month randomized clinical trial, in which two healthcare providers and 50 caregivers of healthy-term infants (4–12 months) in a community health center were recruited. Participants were randomized to usual care or access to the Baby-Feed website, which assesses infants’ diets, provides automated results, and delivers feedback. Measures were assessed at baseline and at the end of the study: diet quality from a validated infant food frequency questionnaire (FFQ), self-reported weight/length to calculate rate of weight gain, and a validated self-efficacy questionnaire. Changes were compared using analysis of covariance or Chi-square/Fisher’s Exact test.</p> Results <p>Baseline characteristics were similar between groups (<i>n</i> = 25 intervention; <i>n</i> = 25 control). Most caregivers were mothers (92%) and Hispanic (86%). Change in total diet quality scores was higher in the intervention (-2.95 ± 6.53) vs. controls (-7.69 ± 7.84; <i>p</i> = 0.031). Healthy weight gain was higher in the intervention group (<i>n</i> = 21, 95%) vs. controls (<i>n</i> = 14, 58%; <i>p</i> = 0.006). Changes in the self-efficacy score for promoting healthy foods were associated with changes in the fruit score (<i>r</i> = 0.46; <i>p</i> = 0.03), and changes in the self-efficacy score for limiting unhealthy foods were associated with changes in the juice score (<i>r</i> = 0.45; <i>p</i> = 0.04) only in the intervention group.</p> Conclusions <p>Using Baby-Feed for 3 months improved diet quality and the rate of weight gain compared with controls in this small and short pilot trial. A larger, longer trial with a more diverse population is needed to confirm the results.</p> Trial Registry <p><a href="https://clinicaltrials.gov/">https://clinicaltrials.gov/</a>: NCT05062824.</p>