Scholarlink

<p>Equine viral arteritis is an economically important contagious disease caused by equine arteritis virus (EAV). Our objective was to evaluate the antiviral activity of indolicidin and K-indolicidin peptides against EAV. We found that indolicidin, but not K-indolicidin, completely inhibits EAV. Furthermore, indolicidin did not affect sperm quality parameters, the primary source of EAV transmission. This is the first report showing the potential of indolicidin as a candidate for use as a therapeutic agent against EAV and an additive in equine semen extenders.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Inactivation of Equine Arteritis Virus by Indolicidin Peptide

  • 期刊论文

  • 发表日期：

    2025年2月17日

查看全文
  • Germán Ernesto Metz,
  • Miriam Beatriz Azcurra,
  • Guilherme Sastre de Souza,
  • Maria Carolina Oliveira de Arruda Brasil,
  • Eduardo Maffud Cilli,
  • Esteban Nicolás Lorenzón

摘要

Equine viral arteritis is an economically important contagious disease caused by equine arteritis virus (EAV). Our objective was to evaluate the antiviral activity of indolicidin and K-indolicidin peptides against EAV. We found that indolicidin, but not K-indolicidin, completely inhibits EAV. Furthermore, indolicidin did not affect sperm quality parameters, the primary source of EAV transmission. This is the first report showing the potential of indolicidin as a candidate for use as a therapeutic agent against EAV and an additive in equine semen extenders.