Context <p>Forest insect outbreaks are major landscape-scale disturbances that shape forest composition and dynamics. In eastern North America, the spruce budworm (SBW) is a key defoliator driving these patterns. Understanding how local forest management interacts with outbreak dynamics at broad spatial extents is crucial for designing sustainable management strategies under climate change.</p> Objective <p>We evaluated whether forest management strategies can modify SBW outbreak development across broad spatial extents and over long time frames.</p> Methods <p>We developed a spatially explicit forest landscape model to simulate SBW outbreaks in Quebec, Canada, over 80&#xa0;years. Simulations were used to compare scenarios with different harvesting rates and regeneration strategies under current and future climate conditions.</p> Results <p>Outbreaks affected from 60,000 to 160,000 km² (11–31% of forest area), with climate change driving a gradual northward shift in maximum outbreak impacts. Annual harvesting of 1% of the forest and promoting non-host regeneration (e.g., trembling aspen) reduced SBW-induced forest mortality by up to 30%, particularly when combined with higher harvest intensities that accelerated species turnover and advanced dampening effects by one to two decades. In contrast, prioritizing host species (e.g., black spruce) had little effect on outbreak patterns.</p> Conclusions <p>Local management strategies can substantially influence large-extent outbreak dynamics if applied consistently and intensively. However, our results highlight that even proactive measures will only partially offset future risks, as climate-driven northward shifts may reduce management effectiveness. Spatially explicit models provide valuable insights to design adaptive forest management that mitigates insect disturbances under climate change.</p> Graphical Abstract <p></p>