<p>Shear-thinning fluids play a key role in pharmaceutical industry for mixing and transportation of chemicals and as a drug delivery carrier in various biomedical devices. This study aims to discuss the flow of shear-thinning nanofluid under the influence of peristalsis and ciliary propulsion in an asymmetric channel. The fundamental conservation laws such as conservation of mass, momentum and energy are applied to develop a mathematical model of the problem. The equations are simplified using normalized variables, stream function and biological valid low Reynolds number and long wavelength assumptions. Mathematica built in solver NDSolve is used to find the numerical solutions for fixed values of involved parameters. The novel features of flow, heat and mass transfer are reported for both cilia-assisted transport and peristaltic transport. The comparison for velocity, temperature and concentration profiles for both linear and full Williamson model is tabulated at different positions of channel and concluded the series truncation in the model influence of the obtained results. Furthermore, the presence of cilia strip assists momentum transport in the central region of the channel. The outcomes of this theoretical study are helpful to design artificial cilia strips, supporting the manufacturing of micro-pumps and microfluidic devices that enhance mixing and particle manipulation, diagnostic tools and therapeutic devices in pharmaceutical and biomedical industry.</p>