Ternary hybrid nanofluids (THNFs) are advanced fluids composed of three distinct types of nanoparticles. These fluids significantly enhance thermal performance by maximizing surface area, improving specific heat capacity, and enabling multifunctional behavior. They can be tailored to achieve high stability, lower viscosity, and superior heat transfer rates, making them ideal for advanced applications such as cooling in electronic devices, automotive systems, and renewable energy technologies. This article delves into the technical details behind THNFs, including their enhanced thermal properties, stability characteristics, and diverse industrial applications. Ethylene glycol \(\left( {{\text{C}}_{{2}} {\text{H}}_{{6}} {\text{O}}_{{2}} } \right)\) and water \(\left( {{\text{H}}_{{2}} {\text{O}}} \right)\) with (50:50 Vol.%) are considered as base fluid while silicon dioxide \(\left( {{\text{SiO}}_{{2}} } \right)\) , aluminum oxide \(\left( {{\text{Al}}_{{2}} {\text{O}}_{{3}} } \right)\) , and copper \(\left( {{\text{Cu}}} \right)\) nanoparticles are considered. Bioconvection phenomenon induced due to gyrotactic microorganisms is considered. Fluid flow is considered by a porous rotating disk. Governing mathematical equations are acquired by accounting the impacts of magnetic field, thermal radiation, activation energy, internal fluid friction, and chemical reaction. The modeled equations are transformed into an ordinary system of differential equations through transformations. Performance of THNF and hybrid nanofluid (HNF) velocity, temperature, mass concentration, and motile density fields are studied through the NDSolve function of Mathematica. Additionally, heat, mass concentration, and motile density transportation rates are computed numerically for THNF and HNF. Results show that motile density field decays versus bioconvection Lewis and Peclet numbers for both THNF and HNF. Improvement in Hartmann number decays tangential and radial velocity profiles while upsurges the thermal field of ternary and dihybrid nanofluid. Contours of THNF and HNF thermal profile accelerate through thermal radiation and dissipative variables while the opposite impact of Prandtl number is noticed. Concentration field of ternary and dihybrid nanofluid profiles retards versus chemical reaction, temperature difference ratio, and Schmidt number whereas an opposite trend is visualized via activation energy variable.