<p>This study presents the synthesis, characterization, and multifunctional evaluation of copper oxide (CuO) nanoparticles doped with zinc (Zn), cobalt (Co), and codoped with both (Zn,Co) using a co-precipitation method. Structural and morphological characterizations were conducted using XRD, FTIR, SEM, UV-Vis DRS, and EDX analysis, confirming the successful doping and formation of monoclinic CuO nanostructures. Antibacterial assays revealed enhanced activity for (Zn,Co)-CuO nanoparticles, with IC₅₀ values as low as 0.45 mg/mL against Klebsiella pneumoniae, indicating superior efficacy due to synergistic metal ion incorporation. DPPH scavenging and albumin denaturation assays demonstrated potent antioxidant and anti-inflammatory properties, with (Zn,Co)-CuO outperforming even standard references. Furthermore, (Zn,Co)-CuO exhibited the highest insecticidal activity (97.75% inhibition) and minimal phytotoxicity, making it a promising biocompatible agent. Photocatalytic degradation studies confirmed the superior efficiency of (Zn,Co)-CuO (91% Eriochrome black T degradation, <i>k</i> = 0.030 min<sup>−1</sup>), attributed to enhanced charge separation and active surface sites. These results collectively highlight the multifunctional potential of (Zn,Co)-CuO nanoparticles in biomedical, agricultural, and environmental applications.</p><p></p>

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Exploring the multifunctionality of co-doped (Zn,Co)-CuO nanoparticles through biological activities, photodegradation, and biotoxicity assessment

  • Muhammad Azam Qamar,
  • Asma Yaqoob,
  • Syed Kashif Ali,
  • Abdullah Ali Alamri,
  • K. F. Hassan,
  • Mohd Imran,
  • Sania Nawaz

摘要

This study presents the synthesis, characterization, and multifunctional evaluation of copper oxide (CuO) nanoparticles doped with zinc (Zn), cobalt (Co), and codoped with both (Zn,Co) using a co-precipitation method. Structural and morphological characterizations were conducted using XRD, FTIR, SEM, UV-Vis DRS, and EDX analysis, confirming the successful doping and formation of monoclinic CuO nanostructures. Antibacterial assays revealed enhanced activity for (Zn,Co)-CuO nanoparticles, with IC₅₀ values as low as 0.45 mg/mL against Klebsiella pneumoniae, indicating superior efficacy due to synergistic metal ion incorporation. DPPH scavenging and albumin denaturation assays demonstrated potent antioxidant and anti-inflammatory properties, with (Zn,Co)-CuO outperforming even standard references. Furthermore, (Zn,Co)-CuO exhibited the highest insecticidal activity (97.75% inhibition) and minimal phytotoxicity, making it a promising biocompatible agent. Photocatalytic degradation studies confirmed the superior efficiency of (Zn,Co)-CuO (91% Eriochrome black T degradation, k = 0.030 min−1), attributed to enhanced charge separation and active surface sites. These results collectively highlight the multifunctional potential of (Zn,Co)-CuO nanoparticles in biomedical, agricultural, and environmental applications.