<p>A metal organic framework (MOF) is a porous crystalline material composed of inorganic metal ions or clusters coordinated to organic ligands, forming a three-dimensional network. These material exhibits high surface area and tunable porosity, making them suitable for various applications. In this study the main objective are the synthesis, characterization and investigation of the effects of gamma ray irradiation on copper-based MOF formed from copper ions (Cu²⁺) and benzene-1,3,5-tricarboxylate (BTC) ligands. The synthesized Cu-BTC MOF was characterized using X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), and Field Emission Scanning Electron Microscopy (FESEM) to evaluate its structural integrity. The sample were subjected to gamma ray irradiation of the dose range is of 0 to 50 kiloGray (kGy). Post irradiation analyses revealed that the MOF regained its structural stability up to 35&#xa0;kGy dose, however beyond this threshold value, the MOF structure have lost their structural as well as electron stability. This finding suggest that Cu-BTC MOFs possess potential for use as radiation resistant material for various applications such as radiation shielding and sensing.</p>