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<p>This study optimized Prussian Blue (PB) synthesis parameters to enhance its binding capacity for thallium (Tl(I)). Using direct (PB-1) and indirect (PB-2) methods, key parameters such as stirring time, drying conditions, oxidant concentration, and iron content were evaluated. For PB-1, the optimal conditions were 12-h stirring, 4-h drying at 60&#xa0;°C, resulting in a maximum binding capacity (MBC) of 200&#xa0;mg/g. For PB-2, the optimal parameters included 2-h drying at 80&#xa0;°C, 20&#xa0;mL oxidant, and 2-h aging at 60&#xa0;°C, yielding an MBC of 208.33&#xa0;mg/g. These findings ensure improved therapeutic efficacy of PB as an active pharmaceutical ingredient. Yes, the street name for the affiliation one is correct</p>

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Optimizing Prussian blue synthesis: exploring the influence of synthesis parameters on maximum binding capacity of Prussian blue for thallium

  • 期刊论文

  • 发表日期：

    2025年1月25日

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  • Vivek Kumar,
  • Riya Mahar,
  • Nidhi Sandal

摘要

This study optimized Prussian Blue (PB) synthesis parameters to enhance its binding capacity for thallium (Tl(I)). Using direct (PB-1) and indirect (PB-2) methods, key parameters such as stirring time, drying conditions, oxidant concentration, and iron content were evaluated. For PB-1, the optimal conditions were 12-h stirring, 4-h drying at 60 °C, resulting in a maximum binding capacity (MBC) of 200 mg/g. For PB-2, the optimal parameters included 2-h drying at 80 °C, 20 mL oxidant, and 2-h aging at 60 °C, yielding an MBC of 208.33 mg/g. These findings ensure improved therapeutic efficacy of PB as an active pharmaceutical ingredient. Yes, the street name for the affiliation one is correct