<p>In this study, the crude oil used is sourced from Zhoucheng Joint Station of the Jiangsu Oilfield. To improve its demulsification performance, a polyether demulsifier, developed using tea polyphenol amine resin as the starting material, is designed based on the characteristics of the crude oil. It features a high molecular weight, strong structural stability, and a multi-branched structure, offering excellent demulsification performance. A series of diblock and triblock polyethers were synthesized via polymerization of ethylene oxide (EO) and propylene oxide (PO) using potassium hydroxide as a catalyst. The demulsifier’s performance was evaluated through dehydration tests and infrared spectroscopy to optimize the synthesis process of the triblock polyether demulsifier. The effects of dehydration time, temperature, dosage, pH and HLB on demulsification performance were investigated The optimal demulsification conditions were identified based on the dehydration rate. The results show that the synthesized demulsifier exhibits good performance for the crude oil used in this study, providing a reference for future demulsifiers research.</p>