Let \(\varvec{S}\) be an \(\varvec{m}\) -system of a ring \(\varvec{R}\) and \(\varvec{P}\) a submodule of a right \(\varvec{R}\) -module \(\varvec{M}\) . This paper presents the notion of \(\varvec{S}\) -prime submodule and provides some properties and equivalent definitions. We define \(\varvec{S}\) -multiplication right module and prove that in multiplication ( \(\varvec{S}\) -multiplication) right \(\varvec{R}\) -module \(\varvec{M}\) , the ideal \(\varvec{(P:}_{\varvec{R}}\varvec{M)}\) is a right \(\varvec{S}\) -prime ideal of \(\varvec{R}\) if and only if \(\varvec{P}\) is an \(\varvec{S}\) -prime submodule of \(\varvec{M}\) . Moreover, we give an \(\varvec{S}\) -version of the prime avoidance lemma. Furthermore, we define \(\varvec{S}\) -finite and \(\varvec{S}\) -Noetherian right modules following the definitions in Abouhalaka, A (Mediterr. J. Math. 21(2), 43 2024). We prove that a multiplication finitely generated right \(\varvec{R}\) -module \(\varvec{M}\) is \(\varvec{S}\) -Noetherian if \(\varvec{(N:}_{\varvec{R}}\varvec{M)}\) is an \(\varvec{S}\) -prime ideal of \(\varvec{R}\) , for all submodules \(\varvec{N}\) of \(\varvec{M}\) . In addition, we give some examples of right \(\varvec{S}\) -Noetherian rings.