Background <p>As traditional tobacco use has declined, the market for novel nicotine products, particularly nicotine pouches, has increased in recent years. This study examines factors associated with nicotine pouch use and their relationship with intentions to quit cigarette smoking.</p> Methods <p>This study utilized nationally representative survey data from the 2022/2023 Tobacco Use Supplement to the Current Population Survey. Multivariable logistic regressions were performed to examine sociodemographic and behavioral factors associated with current nicotine pouch use. Additionally, we assessed whether the use of nicotine pouches was associated with intentions to quit cigarette smoking among current cigarette smokers.</p> Results <p>Current nicotine pouch use was reported by approximately 0.5% of adults, with a higher prevalence (1.2%) in current cigarette smokers. Current nicotine pouch users were significantly more likely to be male, younger, non-Hispanic White, and to use other tobacco products. Among current cigarette smokers, those using nicotine pouches had significantly higher odds of intending to quit smoking within the next 6 months (OR = 1.78, 95% CI = 1.12 – 2.83) and within the next 30 days (OR = 2.09, 95% CI = 1.24 – 3.52).</p> Conclusion <p>Nicotine pouch use is more prevalent among younger, male, non-Hispanic White, and smoking adults. A positive association was found between nicotine pouch use and intentions to quit smoking among current smokers. While popular in specific groups and associated with cigarette quit intentions, these products present both potential public health benefits and risks that warrant continued investigation.</p>