<p>Great progress has been made in the methanol to aromatics (MTA) reaction over ZSM-5 zeolite, the location of Al atoms in ZSM-5 framework is very important for understanding the relationship among structure and activity of catalytic reaction system. In this paper, a series of ZSM-5 zeolites with different acid distribution and Al sites were prepared by changing the tetrapropyl ammonium hydroxide (TPAOH) content in the synthetic gel. When the ratio of TPA⁺/Si increased to 0.4,the results showed that the quantity of Al sites at the channel intersections reach a maximum.This leads to variations in acidity and distribution, and lead to the selectivity of BTX increased from 17.74 to 22.52%, simultaneously. When the ratio of TPA⁺/Si continues to increase to 0.5, the catalytic performance decreases and the BTX selectivity decreases to 13.62%. Therefore, the Al location and synergistic hydrogenation of Brønsted and Lewis acids the performance of ZSM-5 zeolite catalyst, and the zeolite with a higher proportion of Al in the intersection channels shows higher BTX selectivity in the methanol to aromatics reaction. This study elucidates the relationship between the distribution of MTA reaction products and Al sites, establishing the synthesis-structure-performance relationship of zeolite, and providing the experimental basis for rational design of catalysts.</p>