<p>Mpox is a re-emerging zoonotic illness that has raised concerns worldwide because of its outbreak in nonendemic areas, including Kenya. Following the recent outbreak of mpox in Kenya, the Ministry of Health rolled out a public health campaign via social and mainstream media. However, the impact of these campaigns has yet to be assessed. A descriptive cross-sectional study design was adopted, with a total of 5,920 residents randomly selected. A structured and validated questionnaire was used to collect the data. Data were analysed via Stata version 14.0. Descriptive statistics were used to summarize frequencies and proportions, whereas t tests were performed to assess for any significant difference between those exposed to social and mass media campaigns and those not exposed. Regression analysis was used to determine the impact of age, level of education and wealth index on exposure to social and mass media, awareness of the mpox outbreak, knowledge on its preventive measures and reporting channels for suspected cases. A total of 91.1% of the residents in Kiambu County were exposed to at least one social and mass medium, with 62.9% being aware of the mpox outbreak. A total of 54.9% of the residents were aware of at least one correct preventive measure against the disease. 45% knew at least one correct reporting channel for a suspected mpox case. Radio was the greatest source of information and knowledge, at 36.7%. Radio was the best and most effective channel for public health education.</p>