Scholarlink

<p>In this study, a new dialdehyde was synthesized, followed by the successful preparation of a novel naphthalene-based oxa-aza receptor (L). The receptor was structurally characterized using a comprehensive suite of spectroscopic techniques, including UV–Vis, fluorescence, IR, ¹H NMR, ¹³C NMR, DEPT, HSQC, and mass spectrometry. The chemosensor demonstrated high selectivity and sensitivity toward Zn²⁺ ions and the amino acid tyrosine. Fluorescence titration revealed a marked enhancement in emission intensity upon Zn²⁺ coordination, with a 1:1 binding stoichiometry confirmed by Job’s plot and an association constant (K<sub>a</sub>) determined via the Benesi–Hildebrand method. The detection limit for Zn²⁺ was calculated to be 1.86 × 10⁻<sup>8</sup> M. Additionally, the chemosensor exhibited strong affinity for tyrosine, achieving a detection limit of 2.8 × 10⁻<sup>8</sup> M. Fluorescence reversibility studies highlighted the excellent regeneration capability of the chemosensor, underscoring its potential as a reusable probe for biological and environmental monitoring applications.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A Dual-Target Fluorescent Chemosensor Based on Naphthalene Oxa-Aza Receptor for Zn²⁺ and Tyrosine Detection

  • 期刊论文

  • 发表日期：

    2026年5月29日

查看全文
  • Elham Koolivand,
  • Reza Azadbakht,
  • Hassan Keypour

摘要

In this study, a new dialdehyde was synthesized, followed by the successful preparation of a novel naphthalene-based oxa-aza receptor (L). The receptor was structurally characterized using a comprehensive suite of spectroscopic techniques, including UV–Vis, fluorescence, IR, ¹H NMR, ¹³C NMR, DEPT, HSQC, and mass spectrometry. The chemosensor demonstrated high selectivity and sensitivity toward Zn²⁺ ions and the amino acid tyrosine. Fluorescence titration revealed a marked enhancement in emission intensity upon Zn²⁺ coordination, with a 1:1 binding stoichiometry confirmed by Job’s plot and an association constant (Ka) determined via the Benesi–Hildebrand method. The detection limit for Zn²⁺ was calculated to be 1.86 × 10⁻8 M. Additionally, the chemosensor exhibited strong affinity for tyrosine, achieving a detection limit of 2.8 × 10⁻8 M. Fluorescence reversibility studies highlighted the excellent regeneration capability of the chemosensor, underscoring its potential as a reusable probe for biological and environmental monitoring applications.