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<p>This paper reports the development of a fluorescent probe (<b>LD</b>) for selective detection of Fe<sup>3+</sup> in aqueous solution. <b>LD</b> exhibits fluorescence quenching responses toward Fe<sup>3+</sup> with a quenching efficiency of 95%, achieving a detection limit as low as 0.70&#xa0;μM. Notably, its recognition performance remains unaffected by interference from other metal ions. <b>LD</b> forms a 1:1 complex with Fe<sup>3+</sup>, triggering fluorescence quenching via a photoinduced electron transfer (PET) mechanism. <b>LD</b>-loaded test strips and medical cotton swabs enable naked-eye visual detection of Fe<sup>3+</sup>, with colorimetric changes from orange to colorless under UV light. The probe maintains selectivity within the physiological pH range, allowing its application in HeLa cell imaging.</p>

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Fluorescent Probe for Recognizing Fe3+ in Aqueous Solutions and its Applications

  • 期刊论文

  • 发表日期：

    2025年10月21日

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  • Shengling Li,
  • Xiangpeng Kong,
  • Qi Wang,
  • Jinghua Fang,
  • Chenwei Fu,
  • Xinxin Zhang,
  • Jiahui Jia,
  • Yikai Chen

摘要

This paper reports the development of a fluorescent probe (LD) for selective detection of Fe3+ in aqueous solution. LD exhibits fluorescence quenching responses toward Fe3+ with a quenching efficiency of 95%, achieving a detection limit as low as 0.70 μM. Notably, its recognition performance remains unaffected by interference from other metal ions. LD forms a 1:1 complex with Fe3+, triggering fluorescence quenching via a photoinduced electron transfer (PET) mechanism. LD-loaded test strips and medical cotton swabs enable naked-eye visual detection of Fe3+, with colorimetric changes from orange to colorless under UV light. The probe maintains selectivity within the physiological pH range, allowing its application in HeLa cell imaging.