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<p>In this paper, we presents a copper ions (Cu<sup>2+</sup>) and D-fructose biosensing system based on 3-aminophenylboronic acid and salicylaldehyde functionalized hydrothermal carbon spheres (HTCs) as the fluorescent sensor. The sensor system improves the problem of lack of selectivity in the recognition of monosaccharides and copper ions in boronic acid functionalized carbon materials. Use fourier transform infrared spectra (FTIR), elemental analysis, scanning electron microscope (SEM), it confirms the successful grafting of 3-aminophenylboronic acid and salicylaldehyde onto hydrothermal carbon matrix. The proposed sensing system (HTC-Sal-3-APBA-Sal) has been successfully used for the cell labeling and exhibited a fluorescent functionality. The results of the cytotoxicity experiment indicate that the concentration is an important factor for the cytotoxicity of E. 5.0 µM of E is safe for the LTEP-a-2 cells within 112&#xa0;h. In cancer cells, this potential sensing system relies on cell labeling and can play a supporting role in cancer cell-related research.</p>

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3-APBA and Salicylaldehyde-Functionalized Hydrothermal Carbon Materials for Sensing of Cu2+and D-Fructose

  • 期刊论文

  • 发表日期：

    2025年10月29日

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  • Manqing Huang,
  • Dandan Xia,
  • Meng Zhao,
  • Rui Zhang

摘要

In this paper, we presents a copper ions (Cu2+) and D-fructose biosensing system based on 3-aminophenylboronic acid and salicylaldehyde functionalized hydrothermal carbon spheres (HTCs) as the fluorescent sensor. The sensor system improves the problem of lack of selectivity in the recognition of monosaccharides and copper ions in boronic acid functionalized carbon materials. Use fourier transform infrared spectra (FTIR), elemental analysis, scanning electron microscope (SEM), it confirms the successful grafting of 3-aminophenylboronic acid and salicylaldehyde onto hydrothermal carbon matrix. The proposed sensing system (HTC-Sal-3-APBA-Sal) has been successfully used for the cell labeling and exhibited a fluorescent functionality. The results of the cytotoxicity experiment indicate that the concentration is an important factor for the cytotoxicity of E. 5.0 µM of E is safe for the LTEP-a-2 cells within 112 h. In cancer cells, this potential sensing system relies on cell labeling and can play a supporting role in cancer cell-related research.