<p>A novel perimidine derivative: 2-(isoquinolin-1-yl)-1<i>H</i>-perimidine (sensor 1) was synthesized <i>via</i> a facile, one-step reaction between DAN (1,8 diaminonaphthalene) and 2- quinolinecarboxaldehyde. The as-synthesised sensor 1 was found to be stable under a wide <i>pH</i> range of 2–12, and it behaved as a colorimetric as well as fluorescence turn-<i>on</i> sensor for Fe<sup>3+</sup> with a response range varying from 0 to 200 <i>µM</i>. The fluorescence titration profile was used to calculate the binding constant as 1.3 × 10<sup>4</sup> M<sup>−1</sup> and the LOD was as low as 7.4 nM. Additionally, the interference studies revealed the capability of 1.Fe<sup>3<b>+</b></sup> complex to sense Cu<sup>2+</sup>, which was accompanied by the fluorescence turn-<i>off</i> response. The binding constant and detection limit of 1.Fe<sup>3<b>+</b></sup> complex for Cu<sup>2+</sup> were calculated to be 1.44 × 10<sup>3</sup> M and 1.13 × 10<sup>−7</sup> M, respectively. The Fe<sup>3+</sup> induced fluorescence enhancement at different concentrations was also recognized <i>via</i> smartphone, which could benefit in resource-limited areas and could be used as an alternative for complex instrumentation.</p>

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Perimidine Derivative as a Colorimetric/fluorescence turn-on Sensor for Fe3+: Smartphone-assisted Sensing and Quantification of Fe3+

  • Ruhi Mehta,
  • Rajbir Kaur,
  • Navneet Khetrapal,
  • Sanjay Kumar

摘要

A novel perimidine derivative: 2-(isoquinolin-1-yl)-1H-perimidine (sensor 1) was synthesized via a facile, one-step reaction between DAN (1,8 diaminonaphthalene) and 2- quinolinecarboxaldehyde. The as-synthesised sensor 1 was found to be stable under a wide pH range of 2–12, and it behaved as a colorimetric as well as fluorescence turn-on sensor for Fe3+ with a response range varying from 0 to 200 µM. The fluorescence titration profile was used to calculate the binding constant as 1.3 × 104 M−1 and the LOD was as low as 7.4 nM. Additionally, the interference studies revealed the capability of 1.Fe3+ complex to sense Cu2+, which was accompanied by the fluorescence turn-off response. The binding constant and detection limit of 1.Fe3+ complex for Cu2+ were calculated to be 1.44 × 103 M and 1.13 × 10−7 M, respectively. The Fe3+ induced fluorescence enhancement at different concentrations was also recognized via smartphone, which could benefit in resource-limited areas and could be used as an alternative for complex instrumentation.