<p>This paper is devoted to the study of the threshold dynamics for a class of time-delayed reaction diffusion equations in a time-periodic shifting environment which is suitable for survival only in bounded regions. We first establish the spreading properties of solutions under the assumption of uniform asymptotic annihilation. Then we prove a threshold type result on forced time-periodic waves in terms of asymptotic spectral radius. We also obtain a set of sufficient conditions for the uniqueness and stability of such time-periodic waves. At last, we give a lower bound estimate for the asymptotic spectral radius via a Dirichlet boundary value problem.</p>